Ovarian germline stem cells: an unlimited source of oocytes?
نویسندگان
چکیده
منابع مشابه
Genetic and Epigenetic landscape of Germline Stem Cells
Elucidating the critical epigenetics events involved in differentiation and reprogramming of cells to primordial germ cells (PGCs) is among the interesting issues in stem cell research. Here, I will talk about critical transcription factors and global hypomethylation in development of germ cells. Evidence strongly suggests that the earliest PGCs emerging in the E7.25 mouse embryo epiblast have...
متن کاملThe effect of the immune system on ovarian function and features of ovarian germline stem cells
In addition to its role in maintaining organism homeostasis, the immune system also plays a crucial role in the modulation of ovarian function, as it regulates ovarian development, follicular maturation, ovulation and the formation of the corpus luteum. Ovarian germline stem cells are pluripotent stem cells derived from the ovarian cortex that can differentiate into ovarian germ cells and prima...
متن کاملThe Hippo Signaling Pathway Regulates Ovarian Function via the Proliferation of Ovarian Germline Stem Cells.
OBJECTIVE To improve the separation, identification and cultivation of ovarian germline stem cells (OGSCs), to clarify the relationship between the Hippo signaling pathway effector YAP1 and the proliferation and differentiation of OGSCs in vitro and to identify the major contribution of Hippo signaling to ovarian function. METHODS Two-step enzymatic separation processes and magnetic separatio...
متن کاملGermline stem cells.
Stem cells support tissue maintenance by balancing self-renewal and differentiation. Germline stem cells (GSCs) belong to a kind of stem cells that are crucial to development and tissue homeostasis with their ability to both differentiate into gametes and maintain an undifferentiated state by their self-renewal property. The GSCs are unique in that they transmit genetic information from parent ...
متن کاملWisdom Tooth as the Source of Stem Cells
Background Wisdom teeth are usually removed as a routine procedure for therapeutic or prophylactic reasons. Developing wisdom teeth are easy accessible source of stem cells during the adulthood which could be obtained. Methods Search of the PubMed for stem cells and tooth was done. An inclusion criterion was extract of stem cells from wisdom tooth. Results Stem cells can be obtained fro...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2014
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2013.11.009